Unlocking the Potential of Citrus Peels to Tackle Breast Cancer

Unlocking the Potential of Citrus Peels to Tackle Breast Cancer

Breast cancer affects millions of women around the world, and current treatments often rely on hormones to help reduce the risk. But now, researchers are exploring the possibility of using natural compounds from citrus peels to address this issue.

In a recent study, scientists looked at the anti-estrogenic and anti-aromatase activities of ethanolic extracts from citrus peels, as well as eight isolated flavonoids. They found that three of these compounds – naringenin, naringin, and quercetin – had the most potential for reducing the risk of estrogen-dependent breast cancer.

These compounds were then tested in silico, in vivo, and in vitro to assess their anti-estrogenic and anti-aromatase activities. Remarkably, the results showed that these three compounds had the potential to reduce tumor volumes, as well as aromatase levels in solid tumors.

This research suggests that natural compounds from citrus peels could be used to reduce the risk of breast cancer in pre- and post-menopausal women. Although more research is needed to fully understand the potential of citrus peels in tackling breast cancer, this study is a promising start.

In addition to their potential benefits for reducing the risk of breast cancer, citrus peels can also be incorporated into the diet to boost overall health and well-being. Citrus peel is packed with vitamins, minerals, and dietary fiber, making it a great source of nutrition. The flavonoids present in citrus peel also offer antioxidant and anti-inflammatory benefits.

To get the most out of citrus peel, it is important to use the whole fruit, including the peel. Dried, grated citrus peel and citrus zest can be added to salads, smoothies, and other dishes for flavor and added nutrition. The fresh, wet peel can also be used to make teas, infusions, and juice.

Incorporating more citrus peel into the diet can be a great way to enjoy the many health benefits it offers, as well as reduce the risk of breast cancer.


El-Kersh, D. M., Ezzat, S. M., Salama, M. M., Mahrous, E. A., Attia, Y. M., Ahmed, M. S., & Elmazar, M. M. (2021). Anti-estrogenic and anti-aromatase activities of citrus peels major compounds in breast cancer. Scientific reports, 11(1), [7121]. https://doi.org/10.1038/s41598-021-86599-z

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